411 research outputs found

    Renew Design of Traditional Building Complexes with Mat's Strategies

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    The research applies the occidental contemporary notion and modernism designing methods or strategies in renew designing the oriental tradition-building complex. The research involves three aspects of background information: renew design, traditional buildings and mat-building. Renew design, as the guideline, including multiple views and space mode, establishes the cognition, and operational principles of renew design. The traditional building complex, as the object, meaning the normal building complex containing the historic and cultural information, not including the historic and cultural elites and heritages protected by laws, introduces the formal characters, from general planning to the unit and structure, and the diverse values attaching on, which provide the formal reference and operation foundation for the renew design. The mat-building, an architectural phenomenon originated in 1950s, as the method of renew design, supplies the selected operation strategies, matching the formal characters and improving the weakness of traditional building complex. The renew design process carries out in three parts. Preparation, the first part, expounds and proofs the feasibility, superiority and concerning points in renew design, through synthetically comparing the formal characters, values and principles in background information. Renew design process, the second part, following the order of scope, progressively introduces the designing strategies of mat-building into the traditional building complex: integration considers the site as an entirety and prepares for the renew operations; strategies introduce the strategies of mat-building into the site and reorganize the spaces; units transform the original units in traditional building complex to match the characters of that in mat-building; finally, according to the diverse information, improve the arrangement in details. Evaluation, the third part, judges of the outcome of renew design with the standards of renew notions and the values conservation of traditional building complex

    Psychosocial Adjustment of Women with Work-related Disabilities in Rural China

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    The impact of gender roles on the psychosocial adjustment of women in rural China with work related disabilities is explored. The influence of economic reform, traditional family orientation, and gender expectations on the ability of women to work in rural China are discussed via three case studies

    Predicting Oral Disintegrating Tablet Formulations by Neural Network Techniques

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    Oral Disintegrating Tablets (ODTs) is a novel dosage form that can be dissolved on the tongue within 3min or less especially for geriatric and pediatric patients. Current ODT formulation studies usually rely on the personal experience of pharmaceutical experts and trial-and-error in the laboratory, which is inefficient and time-consuming. The aim of current research was to establish the prediction model of ODT formulations with direct compression process by Artificial Neural Network (ANN) and Deep Neural Network (DNN) techniques. 145 formulation data were extracted from Web of Science. All data sets were divided into three parts: training set (105 data), validation set (20) and testing set (20). ANN and DNN were compared for the prediction of the disintegrating time. The accuracy of the ANN model has reached 85.60%, 80.00% and 75.00% on the training set, validation set and testing set respectively, whereas that of the DNN model was 85.60%, 85.00% and 80.00%, respectively. Compared with the ANN, DNN showed the better prediction for ODT formulations. It is the first time that deep neural network with the improved dataset selection algorithm is applied to formulation prediction on small data. The proposed predictive approach could evaluate the critical parameters about quality control of formulation, and guide research and process development. The implementation of this prediction model could effectively reduce drug product development timeline and material usage, and proactively facilitate the development of a robust drug product.Comment: This is a post-peer-review, pre-copyedit version of an article published in Asian Journal of Pharmaceutical Sciences. The final authenticated version is available online at: https://doi.org/10.1016/j.ajps.2018.01.00
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